时间 : 2009-12-07 03:30:17 来源:www.jjpfk.org
摘要目的研究复杂的小腿结节损害疾 7椒ㄓτ昧俅沧橹±砻庖哐Ъ懊庖咦橹Ш脱貉Ъ觳榈取=峁苑⒉《嘤谀行裕饕⑸谒
Studyon1100CasesofCutaneousAllergicNodularVasculitis
HUANGZhengji,SHIHuili,YUBi-e,etal.DepartmentofDermatology,HuaShanHospital,ShanghaiMedicalUniversity,Shanghai200040
Methods Thehaematological,histopathological,immunologicalandimmunohistochemicaldataandmethodswereused.Results (1)Theincidencewashigherinthefemalesthanthatinthemales(6.09:1).(2)Theonsetofthediseasewasmainlyat21~50yearsold(73.36%).(3)Thepredominantclinicalfeaturewassubcutaneousnodularlesionsofthelowerextremities.(4)Theattacksandremissionsofthediseaseseemedtobeinfluencedbytheseasons.(5)Thehistopathologicchangeslimitedinthesubpapillarylayerandsubcutaneoustissue.(6)Theessentialfindingsconsistedofvasculitis,liquefactionnecrosisorgranulomaandgranuloma-likestructure.(7)Thecapillariesandvenuleswereaffectedinallpatientsandtheproliferationofendothelialcellswasmarkedfeature.(8)Theinflammatoryinfiltrateswerepredominantlycomposedoflymphocytesandhistiocytes.(9)Thefibrousseptaofthesubcutaneoustissueshowednonspecificinflammation,whereas,thedermalpapillaeandtheepidermalcellswerenormal.Conclusion Itistheauthors'opinionthatthediseaseisadistinctclinicalentity,cutaneousallergicnodularvasculitis,andthemechanismmightberelatedtodelayedhypersensitivity.
】Vasculitis,allergiccutaneous
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