椋箍у

浠婚锛绉瀛β风
宸ㄧㄨGCA锛涓箍у锛polymyalgiarheumatica锛PMR锛瀵稿筹涓よ绱汉缇や达虫GCA村父瑙PMR骞村涓52.5/10涓浜猴涓鸿タ硅骞翠汉甯歌琛绠＄芥虫ラ涓澶锛戒炽浜婚㈡炬ラ22渚PMR锛骞GCA6渚
寮涔宄ワ涓村椋箍瀛
1957骞Barber棣娆℃洪箍у锛polymyalgiarheurnatica,PMR锛锛杩缁涓村缁煎寰锛琛ㄧ涓洪╄甯楠ㄧ甯肩电‖锛澶瑙浜50宀浠ヤ骞翠汉剁哄跺涓娓妤锛绌惰涓PMR涓HLA-DR4稿筹绀洪浼у芥涔涓澶涓勾榫娉婵绱戒涓瀹稿虫с

浠婚锛绉瀛β风
PMR瀛绌惰灏锛绾PMR骞舵规瀛圭广
寮涔宄ワ涓村椋箍瀛
充PMR瀛绌惰灏杩骞存ワ界舵浜烘ュ澶у宠婊濡搁宠锛瑙ｉｈ讹涓宠娲绘婊娑叉ユ婊浣姝ゅㄤ璁Kyle规惧瀛娓╁害惧惧ф哥56渚涓涓渚绀烘婊涓村涓PMR寰灏惧宠虫涔杩绋浜э涓宠

浠婚锛绉瀛β风
澶уPMRㄣPMR涓村琛ㄧ涓洪ㄣ╄甯楠ㄧ甯哥ㄥ碉浣急涓捐锛娲绘惰氨靛惧姝ｅ父锛ц
寮涔宄ワ涓村椋箍瀛
锛涓锛PMR绐惰捣锛澶ㄦ板ㄥ锛濡涓灞GCA,棰濂姐甯镐即ㄨ韩讹浣涔浣楂瑙╄甯楠ㄧ甯PMR绐虹灞ㄧ讹澶涓哄绉版э涔琛ㄧ涓轰渚ц╅ㄦ楂ㄨ涓肩锛板ㄥ灞冲渚с㈣绔棰ㄨ遍逛害绱杞昏ㄥ靛浜ㄨ捣1锝2灏堕娓娑澶憋浼电‖俱涓ラ涓㈡妇锛涓借┿姊冲ご锛╋涓㈡垮涓涓妤煎伴撅句互涓韫诧存缈昏韩伴鹃у澶寸肩甯歌锛褰卞ｈ浼涓锛PMRｈ涓浠杞诲锛浣ｈ宠肩惰韩娲诲ㄣ虹搴ㄦц缉锛╂楂宠ㄥ磋缉村宠缂╋瀵艰村宠涓诲ㄥ琚ㄨㄩ纰
锛浜锛宠澶瑙浜┿搁宠宸插涓杩般涓杩ц交涓害婊宠ㄥ村便婊宠PMR婊灏寮璧峰稿宠楠ㄨ川惧渚佃锛涓涓被椋箍宠宠甯ㄤ涓ラ绋搴涓灏界稿
琚瀛褰诲ヤ涔β峰绉-绗
椋箍у绉涓村缁煎寰锛圭逛负棰╄甯楠ㄧ甯肩ㄥ点浜崇郴瀵锛骞撮澶50宀浠ヤ锛濂虫ц澶瑙
锛涓锛涓ㄥ碉澶瀵圭Оэ╄甯╁虹讹㈣绔棰ㄣㄨ遍ㄤ甯哥疮
锛浜锛宠锛涓被椋箍у宠甯ㄤ涓ラ绋搴涓锛甯哥疮┿宠
楂涓浠ｅ婚㈣甯歌
锛涓锛ㄨ韩讹涔浣交绛
锛浜锛电‖瀵圭Оу虹ㄨ╄甯棰楠ㄧ甯澶锛╂ㄥ浼撅涓ラ朵戒妇杩╋涓涓妤兼伴撅璧峰伴俱涓锛缉
锛涓锛╁宠宠宠绛澶虹宠
锛锛骞跺棰ㄨ锛虹澶寸澶寸Е瑙妯＄澶辨棰ㄩ存цㄩ纰

浠婚锛绉瀛β风
PMR婊娑插杞诲井ф瑰
寮涔宄ワ涓村椋箍瀛
PMR杞讳腑搴传琛锛ㄥｈ界琛灏胯交搴楂ユф不PMR涓娌锛锛CRP澧楂锛甯镐负瑕璇涔涓PMR涓藉甯歌甯歌锛浣ｈ瀹崇剁郴濡琛娓告讹CPK锛姝ｅ父锛告浣绫婚箍瀛甯搁存с
琚瀛褰诲ヤ涔β峰绉-绗
瑰у楠瀹ゆユ锛绐鸿〃涓鸿娌澧蹇C-搴藉楂杞昏抽搴茬ц传琛借借交搴藉楂杞皑跺纰辨х７搁舵椿ц交搴楂绛
楂涓浠ｅ婚㈣甯歌
锛涓锛琛甯歌锛杞昏充腑搴传琛锛界姝ｅ父ラ锛琛灏垮楂
锛浜锛琛娌澧蹇涓杩50mm/h
锛涓锛C-搴藉楂
锛锛琛娓惰氨姝ｅ父
锛浜锛绫婚箍瀛告浣琛ヤ姝ｅ父
锛娲绘靛炬甯搞

浠婚锛绉瀛β风
PMR璇锛
锛涓锛骞撮50宀锛
锛浜锛棰╄甯楠ㄧ甯3澶ｉㄤ涓冲2澶虹ㄥ碉
锛涓锛瀹楠瀹ゆョずㄨ韩搴锛濡琛娌澧蹇C搴藉楂锛
锛锛绱缇ゆ绾裤涔缉锛
锛浜锛ょ被浼肩剧锛濡RA澶ц㈡ф锛
锛瀵瑰川婵绱搴ソ
寮涔宄ワ涓村椋箍瀛
PMR瀹ㄤ负涓涓村璇50宀浠ヤ骞翠汉浣棰╄甯楠ㄧ甯肩浼存ㄥ碉浣捐绾㈣跨锛缉锛琛娌惧蹇搴楂搴PMR锛浣蹇椤婚ゅ绫讳技PMR琛ㄧ朵剧锛濡绫婚箍宠澶ц㈡ф舵ц跨ょ璇PMR惰椤讳缁瀵绘炬浼村GCA杩硅薄锛ユ锛搴绉浣稿妫ワ涓昏ㄨ娲绘
琚瀛褰诲ヤ涔β峰绉-绗
椋箍у瀹ㄤ负涓村璇搴涓ユ肩浠ヤ6广
锛涓锛骞撮瓒杩50宀
锛浜锛棰╄甯楠ㄧ甯3澶ｉㄤ涓冲2澶虹肩ㄥ碉绋缁1ㄦ浠ヤ
锛涓锛瀹楠瀹ゆョずㄨ韩搴璇濡琛娌惧蹇C-搴藉楂
锛锛绱绾裤缉
锛浜锛ょ被浼艰〃朵剧锛濡绫婚箍у宠㈡ф澶ц舵ц跨ょ
锛瀵瑰川婵绱锛娉煎凹10mg/d锛搴ソ
楂涓浠ｅ婚㈣甯歌
锛涓锛骞撮50宀浠ヤ
锛浜锛缁4ㄤ互涓棰╄甯楠ㄧ甯冲2澶虹电‖
锛涓锛琛娌澶т50mm/h
锛锛灏川婵绱锛濡娉煎凹10-15mg/d俱
锛浜锛ゅ朵剧濡澶ц舵ц跨ゃ绫婚箍宠

浠婚锛绉瀛β风
瀵圭川婵绱搴锛娉煎凹撅榫锛40锝60mg/d锛1ㄥ跺娑澶憋1涓娓7.5锝10mg/d锛缁存1锝2骞达澶у版ｈ瀹ㄧ瑙ｃ棰ソ浣婵绱蹇澶锛婵绱垫骞跺ㄥ跺锛濡叉皑跺ゃ纾烽拌恒纭ょ锛
寮涔宄ワ涓村椋箍瀛
绾PMRㄨ瀹锛榧辨ｈ褰浣杩垮搴ㄦц缉宠杩ㄩ纰瀵瑰绱锛稿浜臣灏兼炬10锝15mg锛搴ソ锛芥弧剁讹骞跺锛绋冲互灏淮1锝2骞达澶颁汉ㄦ不4锝5骞村瀵变PMRㄨ骞村锛搴瀵瑙瀵川婵绱娌荤朵搴杩浣ュ搴ㄥ叉皑跺わMTX锛7.5mg/骞村川婵绱浠浠MTX缁存寰杈濂界PMR濡涓灞涓GCA锛棰濂姐
琚瀛褰诲ヤ涔β峰绉-绗
绯川婵绱不涓昏娈碉芥弧剁讹骞跺瀵逛骞存ｈ锛涓浠瑕锛瑕灏介垮涓搴锛绋冲ㄥ淮锛冲ㄤ弗瀵瑙瀵涓
楂涓浠ｅ婚㈣甯歌
锛涓锛绯川婵绱锛浣涓鸿ф不涓ㄥ臣灏兼10-15mg/d锛4澶╁乏跺缂瑙ｏ琛娌C-搴芥㈠姝ｅ父灏娉煎凹惧5mg/d缁存娌荤锛绋1-2骞淬骞堕ㄨｈ锛搴浜浠ユ臣灏兼40-60mg/d锛剁瑙ｅ娓
锛浜锛句瀵瑰绾с杞荤椋箍уｈ

1锛浠婚锛绉瀛β风锛浜烘虹绀撅2006锛P917
2.寮涔宄ワ涓村椋箍瀛锛涓娴风瀛虹绀撅1999锛P245
3.琚瀛褰诲ヤ涔β峰绉-绗锛灞变绉虹绀撅2002锛P218
4锛涓浠ｅ婚㈣甯歌锛瀹寰界虹绀撅2002锛P241
椋箍у 稿虫绔绔村舵病绔锛瑰昏绔椋箍у 稿冲剧涓浼剧村舵病剧锛瑰昏涓浼剧椋箍у 稿崇剧路棰ㄨWegener借 路告ц借胯绠＄峰法缁ㄨ疯ㄩ夯硅绠＄峰风借ц绠.路澶уぇㄨ 路ゅ琛绠＄风藉姘患寰路缁уㄨ 路惧井涓澶琛绠＄椋箍у 稿崇村舵病稿崇椋箍у 稿抽村路板杩涓涔?濡箍у..zfx109-27路椋箍у濡浣娌荤锛ctt104-29路椋箍у濡浣璇ydj104-29路椋箍у杈╂ワ浼04-29路椋箍у涓村琛ㄧ锛褰04-29路椋箍у锛澶╀腑04-29路浠涔箍у锛fgy104-29路宸ㄧㄨ涓村琛ㄧ锛04-29路宸ㄧㄨ哄讹ㄩ04-29路浠涔法缁ㄨylz704-29椋箍у 锛瀹癸楠璇锛涓娓妤缃浜ゆ涓婚锛（20瀛浠ュ）
（200瀛浠ュ）楠璇锛（绀猴婚杈ラ璇）淇℃渚锛涓戒涓鸿荤渚濡杞浇寮ㄦ绔娑锛璇烽涓浠绯
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