时间 : 2009-12-01 02:18:09 来源:www.ninds.nih.gov
Symptomsofhydrocephalusvarywithage,diseaseprogression,andindividualdifferencesintolerancetothecondition.Forexample,aninfant'sabilitytocompensateforincreasedCSFpressureandenlargementoftheventriclesdiffersfromanadult's.TheinfantskullcanexpandtoaccommodatethebuildupofCSFbecausethesutures(thefibrousjointsthatconnectthebonesoftheskull)havenotyetclosed.
Ininfancy,themostobviousindicationofhydrocephalusisoftenarapidincreaseinheadcircumferenceoranunusuallylargeheadsize.Othersymptomsmayincludevomiting,sleepiness,irritability,downwarddeviationoftheeyes(alsocalled"sunsetting"),andseizures.
OlderchildrenandadultsmayexperiencedifferentsymptomsbecausetheirskullscannotexpandtoaccommodatethebuildupofCSF.Symptomsmayincludeheadachefollowedbyvomiting,nausea,papilledema(swellingoftheopticdiskwhichispartoftheopticnerve),blurredordoublevision,sunsettingoftheeyes,problemswithbalance,poorcoordination,gaitdisturbance,urinaryincontinence,slowingorlossofdevelopmentalprogress,lethargy,drowsiness,irritability,orotherchangesinpersonalityorcognitionincludingmemoryloss.
Symptomsofnormalpressurehydrocephalusinclude,problemswithwalking,impairedbladdercontrolleadingtourinaryfrequencyand/orincontinence,andprogressivementalimpairmentanddementia.Anindividualwiththistypeofhydrocephalusmayhaveageneralslowingofmovementsormaycomplainthathisorherfeetfeel"stuck."BecausesomeofthesesymptomsmayalsobeexperiencedinotherdisorderssuchasAlzheimer'sdisease,Parkinson'sdisease,andCreutzfeldt-Jakobdisease,normalpressurehydrocephalusisoftenincorrectlydiagnosedandneverproperlytreated.Doctorsmayuseavarietyoftests,includingbrainscans(CTand/orMRI),aspinaltaporlumbarcatheter,intracranialpressuremonitoring,andneuropsychologicaltests,tohelpthemaccuratelydiagnosenormalpressurehydrocephalusandruleoutanyotherconditions.
Thesymptomsdescribedinthissectionaccountforthemosttypicalwaysinwhichprogressivehydrocephalusmanifestsitself,butitisimportanttorememberthatsymptomsvarysignificantlyfromonepersontothenext.
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